MSUIR Collection:https://cris.library.msu.ac.zw//handle/11408/9722024-03-28T20:11:02Z2024-03-28T20:11:02ZA Scoping Review of Gut Microbiome and Bifidobacterium Research in Zimbabwe: Implications for Future StudiesDanai T ZhouTaona E MudhluliLindsay J HallJusten ManasaShungu Munyatihttps://cris.library.msu.ac.zw//handle/11408/59172024-03-01T12:33:15Z2023-12-18T00:00:00ZTitle: A Scoping Review of Gut Microbiome and Bifidobacterium Research in Zimbabwe: Implications for Future Studies
Authors: Danai T Zhou; Taona E Mudhluli; Lindsay J Hall; Justen Manasa; Shungu Munyati
Abstract: Background
Gut microbiota play a key role in host health, with certain Bifidobacterium strains critical for immune development. The healthy gut of breastfed infants is dominated by these pioneer microbes, especially the strains that feed on human milk oligosaccharides.
Objective
This is a scoping review of gut microbiome research from Zimbabwe. It focuses on distribution and dynamic changes of bifidobacteria, and milk components that promote growth of microbes in infants, together with the distribution of associated gut microbes in adults.
Design
Online databases were searched for publications from 2000 to 2023.
Results and Analysis
Fourteen publications on microbiota of infants and adults were included in this scoping review. Most were cross-sectional, while three were clinical trials/cohort protocols. Publications focused on pediatrics (78.5%), pregnant women (14.3%), and men (7.2%). Zimbabwe has a high burden of HIV; hence 35.7% of study populations were delineated by HIV status. The laboratory methods used included shotgun metagenomics (62%) or 16S rRNA gene amplicon sequencing. Almost 85% of the studies focused on total microbiome profiles and rarely reported the distribution of different Bifidobacterium species and variants. None of the papers studied human breast milk composition. There were reports of reduced abundance of beneficial genera in pregnant women, children, and adolescents living with HIV. Additionally, gut microbiota was reported to be poorly predictive of child growth and vaccine response, though this was not conclusive.
Conclusion
There are few studies that characterize the gut microbiome by Zimbabwe-based researchers. However, studies on strain level diversity of Bifidobacterium and other key microbes, and their role in health during and beyond infancy, lag behind in Zimbabwe and other low- and middle-income countries. Such cohorts are needed to inform future mechanistic studies and downstream translational work such as next-generation probiotics and prebiotics.2023-12-18T00:00:00ZDanai T ZhouTaona E MudhluliLindsay J HallJusten ManasaShungu MunyatiKnowledge, Attitudes, and Practices of Artisanal and Small-Scale Miners regarding Tuberculosis, Human Immunodeficiency Virus, and Silicosis in ZimbabweDingani MoyoFungai KavengaRonald Thulani NcubeFarai Peter MacheriTariro Christwish MandoFlorence MoyoOrippa MuzvidziwaMpokiseng NcubeHellen MasvingoBlessings ChigarazaAndrew NyamboAlbert MangwanyaRosemary Ncube MwaleTrust MazadzaTinashe MagidiGerald BennyChamunorwa NdudzoVictoria Varaidzo KandidoKudzaishe MutungamiriCollins Timirehttps://cris.library.msu.ac.zw//handle/11408/59142024-02-29T06:58:54Z2023-11-27T00:00:00ZTitle: Knowledge, Attitudes, and Practices of Artisanal and Small-Scale Miners regarding Tuberculosis, Human Immunodeficiency Virus, and Silicosis in Zimbabwe
Authors: Dingani Moyo; Fungai Kavenga; Ronald Thulani Ncube; Farai Peter Macheri; Tariro Christwish Mando; Florence Moyo; Orippa Muzvidziwa; Mpokiseng Ncube; Hellen Masvingo; Blessings Chigaraza; Andrew Nyambo; Albert Mangwanya; Rosemary Ncube Mwale; Trust Mazadza; Tinashe Magidi; Gerald Benny; Chamunorwa Ndudzo; Victoria Varaidzo Kandido; Kudzaishe Mutungamiri; Collins Timire
Abstract: In Zimbabwe, artisanal and small-scale miners (ASMs) have a high prevalence of tubercu-
losis (TB), human immunodeficiency virus (HIV), and silicosis. Previous studies on ASMs utilised
programme data, and it was not possible to understand reasons for the high prevalence of these
comorbidities. We conducted a cross-sectional study to investigate the knowledge, attitudes, and
practices of ASMs regarding TB, HIV, and silicosis. We enrolled a convenience sample of 652 ASMs.
Their mean (standard deviation) age was 34.2 (10.8) years. There were 602 (92%) men and over 75%
had attained secondary education. A total of 504 (80%) of the ASMs knew that TB is a curable disease,
and 564 (87%) knew that they were at higher risk of TB than the general population. However, they
were less likely to know that HIV increases the risk of TB disease, 340 (52%), with only 226 (35%) who
perceived the risk of TB infection to be high among ASMs. Only 564 (59%) were aware that silica dust
causes permanent and incurable lung diseases. Six hundred and twenty (97%) showed a positive
attitude towards healthcare when they were sick, and 97% were willing to use special respirators
to prevent dust inhalation. On practices, only 159 (30%) reported consistent use of either cloth or
respirators to prevent dust inhalation. Three hundred and five (49%) ASMs reported consistent use of
condoms outside their homes and 323 (50%) reported use of water to suppress dust. Only 480 (75%)
of ASMs sought healthcare services when sick. ASMs cited challenges of accessing healthcare services
due to lack of money to pay for healthcare (50%), long distances to clinics (17%), and the shortage of
medicines at clinics (11%). Effective control of TB, silicosis, and HIV among ASMs requires addressing
the identified knowledge gaps and barriers that are faced by ASMs in accessing personal protective
equipment and healthcare services. This will require multisector collaboration and the involvement
of ASMs in co-designing a package of healthcare services that are tailored for them.2023-11-27T00:00:00ZDingani MoyoFungai KavengaRonald Thulani NcubeFarai Peter MacheriTariro Christwish MandoFlorence MoyoOrippa MuzvidziwaMpokiseng NcubeHellen MasvingoBlessings ChigarazaAndrew NyamboAlbert MangwanyaRosemary Ncube MwaleTrust MazadzaTinashe MagidiGerald BennyChamunorwa NdudzoVictoria Varaidzo KandidoKudzaishe MutungamiriCollins TimireFIFA football nurse – A task sharing approach in sports and exercise medicine practice in grassroots women’s football in low- and middle- income settings. A study protocol for a cluster randomised controlled trialNonhlanhla Sharon MkumbuziAndrew MasseySamuel Kiwanuka LubegaBen SorowenEnock Madalitso Chisatihttps://cris.library.msu.ac.zw//handle/11408/58702023-10-16T07:09:52Z2023-09-21T00:00:00ZTitle: FIFA football nurse – A task sharing approach in sports and exercise medicine practice in grassroots women’s football in low- and middle- income settings. A study protocol for a cluster randomised controlled trial
Authors: Nonhlanhla Sharon Mkumbuzi; Andrew Massey; Samuel Kiwanuka Lubega; Ben Sorowen; Enock Madalitso Chisati
Editors: Samuel Bosomprah
Abstract: Football (soccer) is a very popular team sport among African women and girls, with player
numbers continuing to rise at all levels of the sport. Whereas the participation in football and
associated injuries are on the rise, there are not enough sports and exercise medicine
(SEM) personnel to attend to these women football players. While Africa may not currently
have enough SEM trained medical doctors and/or physiotherapists, it has relatively higher
numbers of other healthcare workers; for example, nurses, who lead healthcare services
provision from community to tertiary levels. The primary objective of this study will be to
compare sports medicine practices; injury prevention behaviours; injury risk parameters;
incidence and prevalence of injuries and illnesses in teams with and without a Football
Nurse during one competitive season in Malawi’s Women’s football league. This study will
be a cluster randomised control trial will recruit 24 teams from the Women’s Football League
in Malawi, which will be randomised to either the intervention group or the control group. A
cohort of 12 nurses will receive training in basic football medicine; after which they will be
attached to a total of 12 women’s football teams (intervention group) during one competitive
season. The Football Nurses will be directly report to a physiotherapist or doctor in their dis-
trict to whom they will refer serious injuries for investigations, or further management. The
teams with Football Nurses will be compared to other teams that will not have Football
Nurses. We expect to develop a low cost, sustainable and context relevant solution to man-
age the treatment gap of football injuries/illnesses in underserved communities such as
women’s football.
Description: Trial registration number: Pan African Clinical Trial Registry
(PACTR202205481965514).2023-09-21T00:00:00ZNonhlanhla Sharon MkumbuziAndrew MasseySamuel Kiwanuka LubegaBen SorowenEnock Madalitso ChisatiKnowledge, Attitudes, and Behaviors Toward the Menstrual Cycle and Menstruation Among Elite African Women Football Players, Coaches, Health Personnel, and RefereesFidelis ChibhabhaNonhlanhla S. MkumbuziSenanile B. DlaminiAndreas SernerKatrine Okholm KrygerNatalie BrownBrianna Larsenhttps://cris.library.msu.ac.zw//handle/11408/58652023-10-13T13:24:43Z2023-09-04T00:00:00ZTitle: Knowledge, Attitudes, and Behaviors Toward the Menstrual Cycle and Menstruation Among Elite African Women Football Players, Coaches, Health Personnel, and Referees
Authors: Fidelis Chibhabha; Nonhlanhla S. Mkumbuzi; Senanile B. Dlamini; Andreas Serner; Katrine Okholm Kryger; Natalie Brown; Brianna Larsen
Abstract: Despite cross-cultural differences in knowledge and attitudes toward menstruation, most studies on menstruation in women’s sport have been conducted in high-income countries, such as in Europe, and none have been conducted in Africa. The aim of this study was to explore the knowledge, attitudes, and behaviors of African elite women football players, and their support personnel toward the menstrual cycle and menstruation. An anonymous questionnaire was distributed to all participants (n = 564) at two African women football tournaments. Ultimately, 238 women football players, 44 coaches, 18 health personnel, and 17 referees completed it. From 317 questionnaires analyzed, 17%, 27%, 56%, and 0% of players, coaches, health personnel, and referees, respectively, knew at least one menstrual cycle hormone; 91%, 95%, and 100% of players, coaches, and referees, respectively, did not know at least one menstrual cycle phase. Over 70% of health personnel believed that menstruation negatively affects women’s performance in sports compared with 36% of players; 18%, 28%, and 18% of players, health personnel, and referees, respectively, believed that, for convenience, the menstrual cycle should be changed by drugs like contraceptives; and 54%, 61%, 62%, and 40% of players, coaches, health personnel, and referees, respectively, were confident providing advice about the menstrual cycle to teammates. Minimal knowledge of the menstrual cycle has implications on the development of menstrual cycle considerate training environments and educational materials in African women’s football. Furthermore, the relatively low perceived effect of the menstrual cycle on sporting performance and belief in the use of contraceptives may be attributable to differences in community-level religiocultural and social contexts which influence menstrual experiences, and shape behavioral expectations.2023-09-04T00:00:00ZFidelis ChibhabhaNonhlanhla S. MkumbuziSenanile B. DlaminiAndreas SernerKatrine Okholm KrygerNatalie BrownBrianna Larsen